Diploma Thesis that have been completed or are in progress:
1. Stavroula Balomenou: Study of the action of TGF-b2, bFGF and PDGF-BB growth factors on the biosynthesis of versican in human osteosarcoma cells.
2. Ximerakis Method: Study of the polymorphism of the CYP1A1 detoxification gene of cytochrome P450 in a rural population of Greece exposed to toxic factors.
3. Katerina Vergetaki: Study of the frequency of Q192R polymorphism of the PON1 detoxification gene in a rural population of Crete and its correlation with clinical and pathological parameters.
4. Michalis Spyridon: Study of the distribution of the L55M polymorphism of the PON1 gene in a rural population and its relationship with clinical and pathological parameters.
5. Popi Konstantinou: Study of Q192R and L55M polymorphism of the PON1 detoxification gene in the population of the Peloponnese (Amaliada): correlation with clinical and pathological parameters in combination with exposure to toxic agents (pesticides).
6. Danae Prasianaki: Study of the effect of IGF-I on the expression of syndecans 1, -2 and -4 in human colon cancer cells.
7. Syrogianni Chara: The effects of lumican on Smad signaling in human osteosarcoma cells.
8. Kouvidi Katerina: Study of the action of exogenous CSA chains on the migration and chemotaxis of fibroblasts and fibrosarcoma cells.
9. Posmaraki Phaedra: The effect of heparin on the adhesion of cancer cell lines.
10. Anthi Georgopoulou: Effect of TGFb2 and bFGF growth factors on the adhesion of fibrosarcoma cells as well as on their expression of the heparan sulfate proteoglycans (HSPGs).
11. Vasiliki Papastergiou: Effect of PDGF growth factors and TGF-β in the expression of heparin sulfate proteoglycans and their role in the proliferation of melanoma cells.
12. Eugenia Synolaki: The effect of FGF on the expression of proteoglycans as well as the attachment and migration of normal and cancerous bone cells.
13. Voudouri Kallirroi: The role of the interaction of TGFb2 and their heparin sulafate proteoglycan co-receptor on fibrosarcoma cell attachment.
14. Legatou Marina: The role of low molecular weight heparin (LMWH) in the adhesion of melanoma cells.
15. Giannakis Nikolaos: The role of hyaluronic acid and its receptor, RHAMM, on the adhesive capacity of fibrosarcoma cells.
16. Kavasi Rafaela-Maria: Effect of biglycan on the migratory capacity of osteosarcoma cells.
17. Pitsidianaki Ioanna: The role of the IGF / EGF signaling and estrogen receptors on the functions breast cancer cells. Contribution of the macromolecules of the extracellular matrix.
18. Giarmatziadis Sofia: The role of ERa's expression and interaction with IGF / EGF growth factors on breast cancer cells’ adhesion. Contribution of the extracellular matrix.
19. Zikou Ioanna: The role of the growth factor IGF-I and estradiol (E2) in the proliferation of chondrosarcoma cells of the HTB94 cancer series and the interaction of their signaling pathways.
20. Kourmoulakis Symeon: The role of hyaluronic acid and TLR4 in the activation of keratinocytes by contact allergens.
21. Ftika Stavroula: The effect of caffeine on breast cancer cells functions.
22. Irene-Maria Giatagana: Study of the role of β-catenin/biglycan interaction in the regulation of osteosarcoma cell proliferation.
23. Emmanuela Perisynaki: Study of the action of nanoparticles on the expression of adhesion molecules by HMEC-1 endothelial cells.
24. Nokokyraki Christina-Panagiota: The role of lumican in the regulation of cellular functions of HTB94 chondrosarcoma cells.
INNOvation with GLYcans
Faculty of Medicine, University of Crete Hybrid Symposium 27-29 September
Heraklion, Greece & Zoom Platform Poster, Timetable
"Exploring the Multifaceted Roles of Glycosaminoglycans (GAGs) - New Advances and Further Challenges" Editors
Dr. Dragana Nikitovic
Dr. Serge Perez Website
"The Role of Extracellular Matrix in Cancer Development and Progression" Editors
Professor George Tzanakakis
Professor Dragana Nikitovic Website