1994-1997: Funded by the General Secretariat for Research and Technology, Research Enhancement Program (PENED 1995) for "Malignant Mesothelioma. Biochemical and immunological study of membrane and extracellular proteoglycans related to the action of growth factors with potential application in the diagnosis of disease. Funding amount GRD: 8,000,000 (Participation George Tzanakakis)
2001-2003: Funded by the General Secretariat for Research and Technology, Research Support Program (PENED 2001) for "Breast Cancer. Study of the effect of letrozole aromatase inhibitor and biologically active extracellular space molecules on the functional invasion and metastasis of early hormone-dependent breast cancer. Funding amount: € 112,692 (Participation George Tzanakakis).
2003-2007: Funded by the General Secretariat for Research and Technology, Research Enhancement Program (PENED 2003, project code 03ED 792) for the "Evaluation of new molecules as targets for therapeutic intervention in colorectal cancer: expression of glycosylation profiles and evaluation of their effect on the cancer phenotype. " Funding amount € 56,000 (Supervisor George Tzanakakis).
2005-2007: Funded by the General Secretariat for Research and Technology, Program for Strengthening Research Teams at Universities (ESOP, PYTHAGORAS II, project code KA 2089) for "Study of the action of TGF-b2, PDGF-BB, and bFGF on biosynthesis and secreted proteoglycans in human fibrosarcoma. Funding Amount: 50.000 € (Supervisor George Tzanakakis).
2005-2007: Funded by the General Secretariat for Research and Technology, University Research Enhancement Program (EEOP, PYTHAGORAS II, project code KA 2093) on "Evaluation of HDL / LDL homeostatic proteins and macrophage differentiation prognostic indicators of atherosclerosis”. Funding amount 50,000 € (Participation George Tzanakakis).
2008: Participation in the Pan-European Program "Transmediterranean endoscopic and anatomic surgical training" under Tempous IV (145491-Tempus-2008 FR-JPCR) funded by the EU with: EUR 1,027,082 (Participation George Tzanakakis)
2011-2014: Participation in the Seven Framework Program Cooperation NMP Theme Call identifier: FP-NMP-2011-Large 5 Part B of the proposal. Proposal Full Title “Extended shelf-life biopolymers fr sustainable nd multifunctional food packaging solutions”. Proposal Acronym NanoBarrier Type of Funding Scheme Large-Scale integrating collaborative project. Work Program Topics Addressed NMP-2011.1.1-1 Smart and multifunctional packaging concepts using nanotechnology. Grant Agreement No 280759. Financed by E.U. with EUR 768,225 (Participation George Tzanakakis)
2012-2015: Ministry of Education for Lifelong Learning and Religious Affairs. Operational Program "Thalis, project code D 551- University of Patras - Contribution of intracellular communication of ERα / β with EGF-R and IGF-R in the development and progression of breast cancer: Functional properties of cells, expression of bioactive molecules and ET induction" . Funding Amount: 600.000 € (Participation George Tzanakakis, Dragana Nikitovic).
2013-2014: Ministry of Education for Lifelong Learning and Religious Affairs. Operational Program "Lifelong Learning Education AEI for Upgrading Knowledge of AEI Graduates" code 07.08.73.12.01 Subject: Medical-Pharmaceutical-Biotechnology. Proposal title "Contemporary Diagnostic and Therapeutic Approaches to 21st Century Medicine". Code: 144 16 1.5 2 Higher Education Institution - Beneficiary: University of Crete. Funding amount of the project: 250.000 € (Project Officer George Tzanakakis, Participation Dragana Nikitovic).
2014-2015: Consorzio Milano Ricerche, Italy for Study: "Measurement of changes in hyaluronan metabolism of keratinocytes following exposure to contact DNCB and PPD allergens." KA: 4237. € 2,400. (Supervisor Dragana Nikitovic)
2016-2017: Special Account of the University of Crete (Compact II): “The role of hyaluronan in the activation of keratinocytes by contact allergens.” KA: 4438. 1,500 €. (Supervisor Dragana Nikitovic)
2016-2017: Special Account of the University of Crete (Compact II): "The role of low molecular weight hyaluronan and Toll-like receptors in the activation of keratinocytes by contact allergens." KA: 4569. 1,500 €. (Supervisor Dragana Nikitovic)
2016-2018: ERA.NET Rus Plus grant: “Nanoparticles for Brain Use, Diagnostic and Ophthalmological Applications” (ID # 169, NABUCO). Amount of 200,000 €. (Participation Dragana Nicitovic)
2017-2019: Crete University Special Account (Large Size A): “Dissecting the role of hyaluronan and Toll Like Receptor (TLR) signaling in sterile skin inflammation: new roles for ancient gatekeepers of the immune system.” KA: 4715. 15,000 €. (Supervisor Dragana Nikitovic)
2019-2023: Innovation with Glycans: new frontiers from synthesis to new biological targets - CA18103. (Participation-Full Members George Tzanakakis, Dragana Nikitovic)
2019-2020: University of Crete Special Account (Large size B): “RHAMM, a novel regulator of Wnt / β-catenin signaling in cancer therapy for targeted therapy” KA: 10333. 10,000 €. (Supervisor Dragana Nikitovic)
2018-2022: University of Crete Special Account: "The role of extracellular growth factors and molecules in tumors of mesenchymal origin." KA: 10028. € 40,000. (Supervisor Dragana Nikitovic)
2020-2022: University of Crete Special Account (large size A): “The role of small leucine proteoglycans (SLRPs), biglycan and decorin in osteosarcoma autophagy- dissecting the Janus-faces of cancer cell death processes.” KA: 15.000 €. (Supervisor Dragana Nikitovic)
INNOvation with GLYcans
Faculty of Medicine, University of Crete Hybrid Symposium 27-29 September
Heraklion, Greece & Zoom Platform Poster, Timetable
"Exploring the Multifaceted Roles of Glycosaminoglycans (GAGs) - New Advances and Further Challenges" Editors
Dr. Dragana Nikitovic
Dr. Serge Perez Website
"The Role of Extracellular Matrix in Cancer Development and Progression" Editors
Professor George Tzanakakis
Professor Dragana Nikitovic Website